Lion's mane mushroom (Hericium erinaceus) demonstrates significant cognitive and neurological benefits, supported by both animal and human studies. Research indicates its compounds, such as hericenones and erinacines, stimulate nerve growth factor (NGF) production, crucial for neuronal maintenance and repair[8]. A 16-week human trial involving adults with mild cognitive impairment found that 250 mg lion's mane tablets taken three times daily improved cognitive function scores compared to placebo, suggesting potential in slowing neurodegenerative decline[2][4]. Animal studies further reveal its capacity to regenerate damaged nerve axons, offering promise for nerve injury recovery[2][3]. These neuroprotective properties position lion's mane as a candidate for addressing conditions like Alzheimer’s and Parkinson’s diseases, though larger-scale human trials are needed[4][8].

The mushroom’s immunomodulatory and gastrointestinal benefits are equally compelling. Lion's mane enhances gut microbiota diversity by acting as a prebiotic, fostering beneficial bacteria growth that strengthens the intestinal barrier[1][7]. This effect correlates with reduced inflammation in inflammatory bowel disease (IBD) models, where it suppressed pro-inflammatory cytokines in mice[1][3]. Additionally, its polysaccharides inhibit Helicobacter pylori, a pathogen linked to gastric ulcers, while protecting the stomach lining from NSAID-induced damage[4][7]. Concurrently, lion's mane boosts systemic immunity by activating macrophages and natural killer cells, as observed in studies where it extended survival in mice exposed to lethal pathogens[1][5]. These dual actions on gut and immune health underscore its role in holistic wellness.

Metabolic and cardiovascular benefits round out lion's mane’s therapeutic profile. Animal studies demonstrate its ability to regulate blood glucose via alpha-glucosidase inhibition, mimicking antidiabetic medications, while improving insulin sensitivity in diabetic models[2][6][7]. It also modulates lipid metabolism, reducing triglycerides and LDL cholesterol—key factors in cardiovascular disease risk[3][5]. Antioxidant compounds like hericenone B further mitigate oxidative stress, lowering inflammation implicated in heart disease and cancer[3][5]. Though human trials are limited, these mechanisms suggest potential for managing diabetes and hyperlipidemia, pending further clinical validation[6][7].

Made in the USA

Ingredients: Organic Lion’s Mane (Hericum erinaceus) Mushroom Fruiting Body & Mycelium Powder (Standardized to 40% polysaccharides [400mg]), Vegan Capsule (modified cellulose, water).

Product Amount: 60 vegan capsules

Gross Weight: 0.2lb (90g)

Suggested Use: As a dietary supplement, adults take two (2) capsules daily or as directed by a health care professional. Can be taken with food or on an empty stomach.

Warning: Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.

The Food and Drug Administration has not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease.